Abstract #3200

Quantitative Assessment of Liver Fibrosis using MR-Phase Information

Motohira Mio¹, Tetsuya Yoneda², Kazuki Tani¹, Tatsuo Toyofuku¹, Toshihiro Maeda¹, and Syoichi Morimoto³

¹Department of Radiology, Fukuoka University Chikushi Hospital, Fukuoka, Japan, ²Department of Medical Physics in Advanced Biomedical Sciences, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan, ³Department of Radiology, Fukuoka University Hospital, Fukuoka, Japan

The aim of this study was to evaluate a potential of MR-phase information for a quantification of liver fibrosis. We measured phase value of the liver and examined the correlation between that value and the stage of fibrosis. Additionally, we also evaluate the correlations among phase value and the serum biomarkers of fibrosis and cirrhosis. The phase value showed high statistical correlation to stages of fibrosis, and to be linearly proportional to the following biomarkers; PLT, APRI, FIB-4 index. In conclusion, MR-phase information may is to be a noninvasive quantitative tool for liver fibrosis and its progression.

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