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Abstract #3238

Quantitative dynamic MRI in the phase domain: Characterization of coronary arterial morphology using a simple Fourier method to accurately estimate bolus arrival times in DCE-MRI perfusion imaging

Karl P Kunze1, Teresa Vitadello2, Christoph Rischpler1, Markus Schwaiger1, and Stephan G Nekolla1

1Nuclear Medicine, TU Munich, Munich, Germany, 2Cardiology, TU Munich, Munich, Germany

This abstract proposes a simple method to extract the bolus arrival time (BAT) from myocardial DCE-MRI perfusion data using a low-frequency phase reconstruction of the deconvolution of arterial input functions with myocardial tissue curves. A simulation study is performed to test the proposed technique with respect to accuracy, robustness and superiority to existing approaches. A clinical PET/MRI example and a control group are examined to show the robustness of BAT estimation even without post-processing steps like surface coil intensity correction or saturation correction. The interpretation of the BAT as a surrogate for coronary path lengths is supported by coronary angiography.

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