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Abstract #3239

Validation of the Intravoxel Incoherent Motion Model in the Healthy Human Heart using Black-Blood Preparation

Georg Spinner1, Constantin von Deuster1, Christian Torben Stoeck1, and Sebastian Kozerke1

1Institute for Biomedical Engineering, ETH Zürich, Zürich, Switzerland

In vivo cardiac Intravoxel Incoherent Motion Imaging (IVIM) offers the potential to estimate myocardial perfusion without the need for contrast agents. The IVIM parameter estimates, however, suffer from low signal-to-noise ratio, patient motion and are depending on imaging settings as well as on diffusion gradient shapes. In the present work, further evidence is presented that estimation of perfusion using a second-order motion compensated diffusion weighted sequence in the in vivo human heart is possible.

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