Abstract #3243

Quantitative 3D myocardial perfusion at systole and diastole with a dual echo arterial input function

Jason K Mendes¹, Ganesh Adluru¹, Devavrat Likhite¹, Apoorva Pedgaonkar¹, Merlin J Fair^2,3, Peter D Gatehouse^2,3, Brent Wilson⁴, and Edward V DiBella¹

¹Radiology and Imaging Sciences, University of Utah, Salt Lake City, UT, United States, ²Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, London, United Kingdom, ³National Heart & Lung Institute, Imperial College London, London, United Kingdom, ⁴Cardiology, University of Utah, UT, United States

Quantitative 3D myocardial perfusion is a clinically realistic goal and this work further develops and combines several innovative sequence designs to achieve this goal. These developments include an optimized 3D stack of stars readout (150ms per beat), acquisition and T2* correction of an arterial input function, tailored saturation pulse design and potential whole heart coverage at both systole and diastole at heart rates up to 109 bpm. Implementation and quantitative perfusion results are shown for healthy volunteers and a patient with known coronary disease.

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