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Abstract #3242

Spiral simultaneous multi-slice first-pass myocardial perfusion imaging

Yang Yang1, Matthew Van Houten2, Patrick Norton3, Klaus Hagspiel3, Christopher Kramer1,3, John Mugler2,3, and Michael Salerno1,2,3

1Medicine, University of Virginia, Charlottesville, VA, United States, 2Biomedical Engineering, University of Virginia, Charlottesville, VA, United States, 3Radiology, University of Virginia, Charlottesville, VA, United States

First-pass contrast-enhanced myocardial perfusion imaging is an important tool to assess patients with coronary artery disease, but current techniques are still limited by spatial-temporal resolution and ventricular coverage. Simultaneous multi-slice (SMS) utilizes multi-band (MB) RF pulses which can greatly improve sampling efficiency. We develop an SMS-spiral perfusion pulse sequence by modulating the phase of excitation RF pulses of multiple slices with a Hadamard matrix to achieve significant signal cancellation and an incoherent aliasing pattern. The pulse sequence is evaluated in 23 patients with MB factors of 2, 3 and 4 resulting in high image quality.

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