First-pass contrast-enhanced myocardial perfusion imaging is an important tool to assess patients with coronary artery disease, but current techniques are still limited by spatial-temporal resolution and ventricular coverage. Simultaneous multi-slice (SMS) utilizes multi-band (MB) RF pulses which can greatly improve sampling efficiency. We develop an SMS-spiral perfusion pulse sequence by modulating the phase of excitation RF pulses of multiple slices with a Hadamard matrix to achieve significant signal cancellation and an incoherent aliasing pattern. The pulse sequence is evaluated in 23 patients with MB factors of 2, 3 and 4 resulting in high image quality.
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