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Abstract #3257

Validation of Contrast Enhanced Cine Steady-State Free Precession and T2-Weigthed CMR for Assessment of Ischemic Myocardial Area-At-Risk

Esben Søvsø Szocska Hansen1,2, Steen Fjord Pedersen3, Steen Bønløkke Pedersen4, Hans Erik Stilling Bøtker5, and Won Yong Kim5

1The MR Research Centre, Aarhus University, 8200, Denmark, 2Danish Diabetes Academy, Odense, Denmark, 3Department of Cardiothoracic and Vascular Surgery T, Aarhus University Hospital, 8200, Denmark, 4Department of Endocrinology and Internal Medicine, Aarhus University Hospital THG, Denmark, 5Department of Cardiology, Aarhus University Hospital, 8200, Denmark

Measuring myocardial salvage is important to evaluate the possible cardioprotective effects of adjunctive cardioprotective intervention in patients with myocardial infarction undergoing primary percutaneous intervention. Contrast-enhanced steady-state free precession magnetic resonance imaging (CE-CINE) has recently been used to quantify AAR and validated against myocardial perfusion SPECT. In this study we sought to determine how well T2-STIR and CE-CINE depicts AAR in an experimental porcine model of myocardial ischemia-reperfusion injury using histopathology as the reference for infarct size and AAR.

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