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Abstract #3271

Statistical paradigm for composite MR Angiography generated from multi-contrast MRI

Dahan Kim1,2, Patrick Turski2,3, Oliver Wieben2,3,4, and Kevin M Johnson2,3

1Department of Physics, University of Wisconsin - Madison, Madison, WI, United States, 2Department of Medical Physics, University of Wisconsin - Madison, Madison, WI, United States, 3Department of Radiology, University of Wisconsin - Madison, Madison, WI, United States, 4Department of Biomedical Engineering, University of Wisconsin - Madison, Madison, WI, United States

We present an innovative paradigm to overcome artifacts of individual MR angiography techniques by utilizing complimentary information existing across multi-contrast MR images. This technique applies Bayesian statistics to extract vessel likelihoods from each image type and generates a single ‘composite’ angiogram. Composite angiograms are computed utilizing black blood (BB), contrast enhanced MRA (CE-MRA), and phase contrast MRA (PC-MRA) images acquired in subjects with known neurovascular disease. The composite angiogram is demonstrated to improve vessel lumen depiction overcoming artifacts in individual source images from background enhancement, air cavities, and flow in CE-MRA, BB, and PC-MRA, respectively.

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