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Abstract #3278

Post-Contrast Black-blood HASTE: Initial Results with Ferumoxytol

Takegawa Yoshida1,2, Eun-ah Park1,2, Peng Hu1,2, Kim-Lien Nguyen1,3, and J. Paul Finn1,2

1Diagnostic Cardiovascular Imaging Laboratory, David Geffen School of Medicine at UCLA, Los Angeles, CA, United States, 2Department of Radiological Sciences, David Geffen School of Medicine at UCLA, 3Division of Cardiology, David Geffen School of Medicine at UCLA and VA Greater Los Angeles Healthcare System

Black blood imaging is helpful in cardiovascular evaluation, but is challenging due to its dependence on through-plane blood flow. We explored ferumoxytol-enhanced black-blood Half-Fourier Acquisition Single-shot Turbo Spin-echo (HASTE) imaging for cardiovascular morphologic evaluation and compared its effectiveness with pre-contrast double inversion (DIR) HASTE. Post-ferumoxytol HASTE showed complete and homogeneous blood suppression and better qualitative image scores (all, p<0.001) for all cardiovascular regions. The technique holds promise for confident definition of thrombus or plaque, independently of blood flow.

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