Our goal was to determine if the cortico-medullary Apparent Diffusion Coefficient difference (ΔADC), that previously exhibited a strong correlation with renal fibrosis, is independent of MR system. Comparison of ADC (cortex, medulla and Δ) over Siemens (1.5T AERA, 3T PRISMA, 3T SKYRA) and Philips (1.5T INGENIA, 3T PET-MR) systems was carried out in eight volunteers. Significant ADC differences were measured for the cortex and medulla independently using PRISMA and AERA and, for cortex of AERA and INGENIA (p<0.05). ΔADC corrected inter-scanner variability with no significant differences across all MR systems (p>0.05).
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