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Abstract #3350

Applied Gradient Nonlinearity Correction for Quantitative Diffusion MRI

Baxter P Rogers1, Allen T Newton1, E Brian Welch1, Jeffrey J Luci2, Heidi A Edmonson3, and Bennett A Landman4

1Vanderbilt University Medical Center, Nashville, TN, United States, 2University of Texas at Austin, 3Mayo Clinic, 4Vanderbilt University

Accurate and reliable quantitative diffusion MRI depends on correcting for spatially varying errors in applied diffusion gradients due to nonlinearity of the gradient coil fields. We measured the temporal and inter-scanner variability of a phantom-based correction protocol on four different scanners. Estimated errors in diffusion gradient b-value and direction were significant, and differed between scanners. Scanner differences in temporal stability indicated the need for site-specific calibrations.

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