During postnatal brain development brain structures undergo large changes in size, shape, composition and microstructural appearance. Diffusion tensor imaging (DTI) is an MRI modality particularly informative on white matter. We perform tensor based morphometry (TBM) using deformation fields constructed using all scalar and directional information provided by diffusion tensor data (DTBM) to measure volumetric changes of brain structures from neonate to adulthood. Our results indicate that DTBM reveals interesting patterns in the developmental trajectories for different structures in the human brain. This information would be important to characterize deviation from normal developmental patterns due to developmental delay or other disorders.
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