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Abstract #3388

Phase retrieval from q-space imaging for diffusion pore imaging

Kerstin Demberg1, Frederik Bernd Laun1,2, Peter Bachert1, Dieter Höpfel3, and Tristan Anselm Kuder1

1Medical Physics in Radiology, Deutsches Krebsforschungszentrum (DKFZ, German Cancer Research Center), Heidelberg, Germany, 2Institute of Radiology, University Hospital Erlangen, Erlangen, Germany, 3Electrical Engineering & Information Technology, Karlsruhe University of Applied Science, Karlsruhe, Germany

Diffusion pore imaging enables the detection of the average shape of arbitrary closed pores in an imaging volume element. Until now, an experimentally challenging phase measurement, either by measuring with a long-narrow gradient profile or by employing double diffusion encodings, was a prerequisite to obtain the full information on the Fourier transform of the pore image. In this study, we present a first experiment, where the phase information is recovered alone from the magnitude information acquired by q-space imaging. To solve this phase problem, we adopted a phase retrieval algorithm that is widely applied to X-ray diffraction data.

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