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Abstract #3406

Origin of diffusion anisotropy in human kidney: a combined DTI and IVM study

Sophie van Baalen1, Bart Vroling1, Martijn Froeling2, and Bennie ten Haken1

1Faculty of Science and Technology, University of Twente, Enschede, Netherlands, 2Radiology, University Medical Centre Utrecht, Utrecht, Netherlands

To visualize the anisotropy of diffusion and pseudodiffusion, we have performed a two-tensor fit (D and D*) on IVIM data in healthy volunteers. We have performed tractography on both tensors and compared the results with tractography perfomed using a conventional DTI tensor fit. Tracking was possible using both D and the D* derived tensors and resulted in patterns similar to conventional tractography. We conclude that diffusion and pseudodiffusion both have an anisotropic component that can be visualized using tractography, which indicates that they both likely contribute to the coherent diffusion anisotropy that is detected in conventional monoexponential DTI.

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