Abstract #3429

Determination of Droplet Size Distribution in Brown Adipose Tissues by Diffusion NMR Spectroscopy

Sanjay Kumar Verma¹, Jadegoud Yaligar¹, Navin Michael², Tian Xianfeng¹, Venkatesh Gopalan¹, Suresh Anand Sadananthan², Rengaraj Ananthraj¹, and S. Sendhil Velan^1,2

¹Laboratory of Molecular Imaging, Singapore Bioimaging Consortium, Singapore, Singapore, ²Singapore Institute for Clinical Sciences, Singapore

Non-Invasive Imaging of Brown Adipose Tissue is of significant interest due to its potential to combat obesity and diabetes. In this study, we have utilized diffusion spectroscopy to estimate the droplet size distribution in chow and high-fat diet fed brown adipose tissues obtained from rodents. The high-fat diet BAT exhibited reduction in the restriction due to the increase in droplet size. The histology results confirm the droplet size distribution in both control and high-fat diet tissues.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.