Abstract #3433

Clinical evaluation of the early renal hypoxia in Type 2 Diabetes based on BOLD-MRI

Junjie Ren¹, Shengzhang Ji¹, Chunxia Li², Zhizheng Zhuo³, and Hao Wang¹

¹The 4th center hospital of TianJin, Tianjin, People's Republic of China, ²Inner Mongolia people's hospilal, Inner Mongolia, People's Republic of China, ³Philips Healthcare, Beijing, People's Republic of China

Till now the type 2 diabetes (T2DM) is more and more prevalent, and diabetic nephropathy (DN) has become the main leading cause of end-stage renal disease (ESRD). However the onset of DN is always ambiguous. In recent years, many studies focused on the change of renal oxygenation in diabetes and showed renal hypoxia especially in medulla. Blood oxygen level dependent magnetic resonance imaging (BOLD-MRI) is a non-invasive method that can assess hypoxia in prostate gland by utilizing the endogenous contrast generated by paramagnetic deoxyhemoglobin.

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