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Abstract #3433

Clinical evaluation of the early renal hypoxia in Type 2 Diabetes based on BOLD-MRI

Junjie Ren1, Shengzhang Ji1, Chunxia Li2, Zhizheng Zhuo3, and Hao Wang1

1The 4th center hospital of TianJin, Tianjin, People's Republic of China, 2Inner Mongolia people's hospilal, Inner Mongolia, People's Republic of China, 3Philips Healthcare, Beijing, People's Republic of China

Till now the type 2 diabetes (T2DM) is more and more prevalent, and diabetic nephropathy (DN) has become the main leading cause of end-stage renal disease (ESRD). However the onset of DN is always ambiguous. In recent years, many studies focused on the change of renal oxygenation in diabetes and showed renal hypoxia especially in medulla. Blood oxygen level dependent magnetic resonance imaging (BOLD-MRI) is a non-invasive method that can assess hypoxia in prostate gland by utilizing the endogenous contrast generated by paramagnetic deoxyhemoglobin.

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