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Abstract #3434

Characterization of brown and white adipose tissue in 7-year old children

Jonathan Andersson1, Emma Kjellberg2,3, Elin Lundström1, Mathias Engström4, Josefine Roswall2,3, Stefan Bergman5, Pär-Arne Svensson6, Håkan Ahlström1,7, Jovanna Dahlgren2, and Joel Kullberg1,7

1Department of Radiology, Institution of Surgical Sciences, Uppsala University, Uppsala, Sweden, 2Department of Pediatrics, the Institution of Clinical Sciences, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden, 3Department of Pediatrics, Halland Hospital, Halmstad, Sweden, 4Applied Science Laboratory, GE Healthcare, Uppsala, Sweden, 5Primary Health Care Unit, Department of Public Health and Community Medicine, Institute of Medicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden, 6Department of Pediatric Radiology, The Sahlgrenska University Hospital, Gothenburg, Sweden, 7Antaros Medical, Mölndal, Sweden

The purpose of this study was to characterize and compare brown and white adipose tissue in 7 year-old overweight/obese and normal weight children using whole-body water-fat MRI. Correlations were also performed between the brown adipose tissue measurements and other measurements, such as VAT and SAT volumes. Results overall showed expected differences and associations to several measures relevant for obesity. We conclude that whole-body water-fat MRI of 7 year-old children is feasible and allows characterization of brown and white adipose tissue.

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