Abstract #3450

Longitudinal Assessment of Visceral and Subcutaneous Adipose Tissue in Obese Patients undergoing Weight Loss Surgery

Curtis N Wiens¹, Cristobal Arrieta², Ignacio Osorio², Ben Ratliff¹, Timothy J Colgan¹, Alan B McMillan¹, Nathan S Artz^1,3, Luke Funk⁴, Guilherme M Campos^4,5, Jacob Greenberg⁴, Daniela Esparza², Sergio Uribe^6,7, Claude B Sirlin⁸, and Scott B Reeder^1,9,10,11,12

¹Radiology, University of Wisconsin, Madison, WI, United States, ²Electrical Engineering, Pontificia Universidad Catolica de Chile, Santiago, Chile, ³Diagnostic Imaging, St. Jude Children's Research Hospital, Memphis, TN, United States, ⁴Surgery, University of Wisconsin, Madison, WI, United States, ⁵Surgery, Virginia Commonwealth University, Richmond, VA, United States, ⁶Radiology, Pontificia Universidad Catolica de Chile, Santiago, Chile, ⁷Biomedical Imaging Center, Pontificia Universidad Catolica de Chile, Santiago, Chile, ⁸Radiology, University of California, San Diego, CA, United States, ⁹Medical Physics, University of Wisconsin, Madison, WI, United States, ¹⁰Medicine, University of Wisconsin, Madison, WI, United States, ¹¹Emergency Medicine, University of Wisconsin, Madison, WI, United States, ¹²Biomedical Engineering, University of Wisconsin, Madison, WI, United States

This work monitored longitudinal changes in visceral (VAT) and subcutaneous (SCAT) adipose tissue in response to weight loss. Twenty-one patients undergoing clinical weight loss surgery (WLS) were recruited for 5 MRI studies: 2-3 weeks prior, 1 day prior to WLS and 1, 3, and 6 months post-WLS. Single breath-hold, chemical shift encoded acquisitions were analyzed using an Osirix semi-automated segmentation software to monitor changes in VAT and SCAT volumes. Continual reductions in VAT and SCAT were measured over the five visits. At every visit, each patient’s relative body fat distribution remained relatively constant despite overall reductions in both VAT and SCAT.

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