Studies performing diffusion-weighted MRI on anisotropic fibre phantoms suffer from microscopic background field gradients induced by differences in the magnetic susceptibility of the employed materials. We present a particularly promising approach that makes use of a matched magnesium chloride solution to eliminate these effects. The method is thoroughly studied and successfully validated on a crossing-fibre phantom containing two perpendicularly crossing fibre populations. The obtained results are no longer subject to any orientation-dependence with respect to B0.
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