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Abstract #3475

Structure tensor informed fibre tractography at 3T

Kwok-shing Chan1, David G. Norris1, and José P. Marques1

1Donders Centre for Cognitive Neuroimaging, Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Netherlands

Structure tensor informed fibre tractography (STIFT) based on diffusion images at 3T and gradient-echo images at 7T has shown improvement in the accuracy of white matter bundles tracking in the presence of kissing and crossing fibres. In this study, we implemented STIFT using both DWI and GRE images at 3T. We further demonstrated white matter contrast presence in T2* mapping and quantitative susceptibility mapping derived from GRE data can be used to compute structure tensor. The benefits of STIFT are shown in two tractography applications.

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