An accurate delineation of the optic radiation (OR) is useful in reducing the risk of a visual field deficit after temporal lobe resective surgery. However, tractography, especially of the probabilistic kind, is prone to generate spurious (false-positive) streamlines that are poorly aligned with the surrounding bundle. Fiber-to-bundle coherence measures are applied to identify and remove spurious fibers, which together with test-retest parameter estimation can provide a reconstruction of the OR that is robust to the stochastic realization of probabilistic tractography. Pre- and post-operative comparison of the OR is performed for epilepsy patients to quantify the accuracy of damage prediction.
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