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Abstract #3495

Inferior Fronto-occipital Fasciculus Tractography —— a Comparison of Reconstruction Methods

Ting Gong1, Qiqi Tong1, Hongjian He1, Qiuping Ding1, and Jianhui Zhong1

1Center for Brain Imaging Science and Technology, Department of Biomedical Engineering, Zhejiang University, Hangzhou, People's Republic of China

The anatomical definition and functional role of inferior fronto-occipital fascicle (IFOF) in human brain are important but still controversial. Post-mortem dissection has provided detailed and extended cortical terminations of IFOF while diffusion tractography further facilitates the definition of extended terminations through in vivo studies. A careful comparison of fiber reconstruction methods including diffusion tensor imaging, q-ball imaging, generalized q-sampling imaging and diffusion kurtosis imaging (DKI) was conducted. More integrated IFOF tracts were found with DKI, which could benefit the exploration of precise terminations of IFOF, thus a better understanding of its function.

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