Abstract #3505

Quantitative Noise Analysis for Increased Homogeneity in Intra-voxel Incoherent Motion (IVIM) Perfusion Imaging in Brain

Harri Merisaari^1,2 and Christian Federau³

¹Turku PET Centre, Turku University Central Hospital, Turku, Finland, ²Department of Information Technology, University of Turku, Turku, Finland, ³Department of Radiology, Uniklinik Balgrist, University Zürich, Zürich, Switzerland

Intravoxel incoherent motion (IVIM) perfusion imaging has been shown to be applicable in clinical brain examinations, but those images are known to be noisy. To better quantify the necessary conditions to produce homogenous IVIM perfusion images in the brain, we studied the properties of signal noise as function of b-value and of localization in the brain. We compared the image quality of the perfusion maps as function of number of average to the maximal quality IVIM perfusion maps obtained during a 1 hour acquisition time.

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