Abstract #3559

Assessment of Liver Function of HBV-induced Cirrhosis using T1 Mapping on Gd-EOB-DTPA-Enhanced MRI

Xueqin Zhang¹, Jian Lu¹, Tao Zhang¹, Jifeng Jiang¹, Ding Ding¹, Sheng Du¹, and Weibo Chen²

¹Nantong Third People’s Hospital, Nantong University, Nantong, People's Republic of China, ²Philips Healthcare, Shanghai, People's Republic of China

The purpose of this study was to investigate the ability of T1 mapping on Gd-EOB-DTPA-enhanced MRI for the assessment of liver function of HBV-induced cirrhosis. We used Look-Locker sequences to acquire T1 mapping images pre and post-contrast at 5, 10, 15 and 20 minutes after Gd-EOB-DTPA administration, T1 relaxation times of the liver parenchyma were measured, reduction rates of T1 relaxation times between pre- and post-contrast enhancement were calculated, our study showed that Gd-EOB-DTPA-enhanced T1mapping MRI is useful for the evaluation of Liver function of HBV-induced cirrhosis.

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