Abstract #3571

Engineered Protein-Iron Oxide Hybrid Biomaterial for MRI-monitoring of Drug Delivery

Lindsay Kathleen Hill^1,2,3, Che Fu Liu³, Teeba Jihad³, Youssef Zaim Wadghiri², and Jin Kim Montclare^3,4

¹Biomedical Engineering, SUNY Downstate Medical Center, Brooklyn, NY, United States, ²Radiology, New York University School of Medicine, New York, NY, United States, ³Chemical and Biomolecular Engineering, New York University Tandon School of Engineering, Brooklyn, NY, United States, ⁴Chemistry, New York University, New York, NY, United States

Our goal is to create protein engineered biomaterials for dual drug delivery and MRI monitoring to improve the growing field of theranostics. Here we present a drug binding protein that is templated to USPIOs using a biomineralization-inspired biotemplation method. The agent shows promise for T2/T2*-weighted MRI.

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