QSM is able to provide high contrast for iron-rich deep-brain nucleus. This is attributed to the sensitivity of magnetic susceptibility to the spatial variations of cellular components that exhibit different magnetic susceptibility properties, especially for brain iron and myelin. Although there have been atlases proposed for certain age groups, a longitudinal statistical atlas construction from general healthy population based on QSM is still lacking. We constructed longitudinal QSM atlases over the whole lifespan (from 1 to 83 years-old). One common QSM atlas is built for every 10-years interval to demonstrate the unique age-specific morphology and appearance of human brains.
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