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Abstract #3691

Echo Planar Spectroscopic Imaging of Hyperpolarized 13C in a Clinical System with Reduced Chemical Shift Artifacts

Abubakr Eldirdiri1,2, Stefan Posse3,4,5, Lars G. Hanson1,2, Rie B. Hansen1, Adam E. Hansen6, and Jan Henrik Ardenkjær-Larsen1

1Center for Hyperpolarization in Magnetic Resonance, DTU Elektro, Technical University of Denmark, Kgs. Lyngby, Denmark, 2Danish Research Center for Magnetic Resonance, Hvidovre Hospital, Hivdovre, Denmark, 3Department of Neurology, University of New Mexico, Albuquerque, NM, United States, 4Department of Physics and Astronomy, University of New Mexico, Albuquerque, United States, 5Department of Electrical and Computer Engineering, University of New Mexico, Albuquerque, United States, 6Department of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet, Copenhagen, Denmark

Fast and robust symmetric echo planar spectroscopic imaging sequence for hyperpolarized 13C in a clinical system is presented. The sequence employs a reconstruction algorithm that re-grids the sampled data in the spatio-temporal frequency space to compensate for the chemical shift artifacts and achieve an improved reconstruction within a limited bandwidth. The sequence was tested on a clinical 3 T whole body scanner using dedicated 13C coils and was compared with the conventional chemical shift imaging. Good tradeoff between speed, efficiency and SNR was achieved and the reconstruction was superior compared to the commonly used FFT reconstruction.

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