Abstract #3691

Echo Planar Spectroscopic Imaging of Hyperpolarized 13C in a Clinical System with Reduced Chemical Shift Artifacts

Abubakr Eldirdiri^1,2, Stefan Posse^3,4,5, Lars G. Hanson^1,2, Rie B. Hansen¹, Adam E. Hansen⁶, and Jan Henrik Ardenkjær-Larsen¹

¹Center for Hyperpolarization in Magnetic Resonance, DTU Elektro, Technical University of Denmark, Kgs. Lyngby, Denmark, ²Danish Research Center for Magnetic Resonance, Hvidovre Hospital, Hivdovre, Denmark, ³Department of Neurology, University of New Mexico, Albuquerque, NM, United States, ⁴Department of Physics and Astronomy, University of New Mexico, Albuquerque, United States, ⁵Department of Electrical and Computer Engineering, University of New Mexico, Albuquerque, United States, ⁶Department of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet, Copenhagen, Denmark

Fast and robust symmetric echo planar spectroscopic imaging sequence for hyperpolarized ¹³C in a clinical system is presented. The sequence employs a reconstruction algorithm that re-grids the sampled data in the spatio-temporal frequency space to compensate for the chemical shift artifacts and achieve an improved reconstruction within a limited bandwidth. The sequence was tested on a clinical 3 T whole body scanner using dedicated ¹³C coils and was compared with the conventional chemical shift imaging. Good tradeoff between speed, efficiency and SNR was achieved and the reconstruction was superior compared to the commonly used FFT reconstruction.

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