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Abstract #3692

Multi-echo balanced steady state imaging of hyperpolarized [1-13C]-pyruvate at 9.4T

Christian Ƙstergaard Mariager1, Mette Ji Riis-Vestergaard1, Haiyun Qi1, Steffen Ringgaard1, and Christoffer Laustsen1

1Department of Clinical Medicine, The MR Research Centre, Aarhus University Hospital, Aarhus N, Denmark

Hyperpolarized (HP) [1-13C]-pyruvate imaging has gained increasing attention, as its ability to monitor metabolic changes in real-time is expected to have a great clinical impact. In this work we investigate the use of a fast multi-echo balanced steady state free precession (BSSFP) sequence to acquire spectroscopic images at 9.4T. We show that this technique, in combination with the iterative Dixon type reconstruction technique (IDEAL), yields dynamic high resolution spectroscopic maps in a 1H phantom as well as for preliminary in vivo HP [1-13C]-pyruvate experiments in rat kidneys.

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