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Abstract #3695

Dynamic shimming for multi-slice hyperpolarized metabolic imaging of the rat heart at 9.4T

Patrick Wespi1, Jonas Steinhauser1, Grzegorz Kwiatkowski1, and Sebastian Kozerke1

1Institute for Biomedical Engineering, ETH and University Zurich, Zurich, Switzerland

In this work dynamic shimming was implemented for multi-slice hyperpolarized metabolic imaging of the rat heart at 9.4T. Phantom experiments were carried out to test the switching between different shim sets and eddy current effects. The method was subsequently applied to assess cardiac metabolism in healthy rats after injecting hyperpolarized [1-13C] pyruvate. It is demonstrated that B0 inhomogeneity induced signal variations could be reduced with dynamic shimming when compared to static shimming.

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