In this work rapid decarboxylation of [1,2-13C]pyruvate using hydrogen peroxide was employed to obtain hyperpolarized [1-13C]acetate. 13C polarization was transferred completely and reproducibly. The application of the concept is demonstrated for detecting [1-13C]acetate and [1-13C]acetylcarnitine in the in-vivo heart.
This abstract and the presentation materials are available to members only; a login is required.