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Abstract #3798

A novel MR-based framework for subject-specific guidance of TMS treatments

Stefano Mandija1, Petar I Petrov2, Jord JT Vink2, Sanne Schuite-Koops2, Peter R Luijten1, Cornelis AT van den Berg1, and Sebastian FW Neggers2

1Center for Image Sciences, UMC Utrecht, Utrecht, Netherlands, 2Rudolf Magnus Institute of Neuroscience, UMC Utrecht, Utrecht, Netherlands

In the field of neurostimulation, Transcranial Magnetic Stimulation is gaining more and more momentum since it allows direct control on brain activation in a non-invasive and non-painful manner. However, accuracy of TMS administrations and precise knowledge on its biological effects are still limited. To better understand TMS induced effects, we propose a novel combined TMS-MRI framework which allows us to map the TMS induced magnetic field and to map subject-specific brain activation by means of concurrent TMS-MRI measurements. These subject-specific measurements, will allow us to validate neuronal models which are currently used to predict TMS induced brain activations.

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