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Abstract #3802

Differential modulation of arterial and venous oxygenation through inhalation of carbogen (95%O2/5%CO2) vs. 100% O2.

Harshan Ravi1, Wen-Tung Wang1, Dzung Pham1, and John Butman1,2

1Center for Neuroscience and Regenerative Medicine, National Institute of Helath, Bethesda, MD, United States, 2Radiology and imaging sciences, National Institute of Helath, Bethesda, MD, United States

Susceptibility-weighted imaging (SWI) is a MRI sequence which exploits the susceptibility contrast between various tissues by incorporating MRI phase data. In some clinical applications it may be useful to increase such contrast (e.g. identification of plaque associated veins) and in other cases it may be useful to suppress or decrease such contrast (e.g. visualization of microhemorrhage). Here we explore the use of gas inhalation (oxygen and carbogen) to modulate the conspicuity of brain vasculature.

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