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Abstract #3917

Interaction between trajectory deviations and B0 field inhomogeneity in readout-segmented EPI and spiral imaging

Yoko A Spirig1,2, Nadine N Graedel2, Lars Kasper1, Karla L Miller2, Robert Frost2, Stuart Clare2, Klaas P Pruessmann1, and S Johanna Vannesjo2

1Institute for Biomedical Engineering, University of Zurich and ETH Zurich, Zurich, Switzerland, 2FMRIB centre, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom

We studied the effect of encoding imperfections due to gradient errors with a focus on their interaction with $$$B_0$$$ inhomogeneities. Using a simulation framework, we retrospectively sampled data using k-space trajectories of two fast imaging sequences and compared reconstructions based on nominal, gradient impulse response (GIRF) predicted and measured (ground-truth) trajectories for spiral and readout-segmented EPI sequences. We found that the detrimental impact of trajectory imperfections on image quality is strongly amplified by $$$B_0$$$ inhomogeneities, especially for non-Cartesian trajectories. Furthermore, we confirmed that GIRF-predicted trajectory based reconstructions (requiring only a one-time calibration) allow effective artifact reduction.

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