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Abstract #4038

Utilization of T1ρMR imaging in Sjögren’s syndrome with normal appearing parotid glands: initial findings

Zhengyang Zhou1, huayong zhang2, and Weibo Chen3

1Department of Radiology, Drum Tower Hospital, School of Medicine, Nanjing University, Nanjing, People's Republic of China, 2Department of Rheumatology, Drum Tower Hospital, School of Medicine, Nanjing University, People's Republic of China, 3Philips Healthcare, Shanghai, People's Republic of China

Sixteen SS patients and age- and gender- match healthy volunteers underwent parotid MR imaging to evaluate whether T1ρ values could diagnose of SS patients. T1ρ values between the patients and healthy volunteers were compared. ROC analysis was used to evaluate the diagnostic performance of the T1ρ values. The T1ρ values of SS patients were significantly higher than those of healthy volunteers. With a cutoff value of 88.02 ms, the diagnostic sensitivity and specificity of the parotid T1ρ value was 75.0% and 100.0%, respectively. Parotid T1ρ MR imaging held the potential in the diagnosis of SS without morphological changes of glands.

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