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Abstract #4045

High Resolution Steady State Diffusion and Magnetization Transfer Imaging of the Spinal Cord

Matthias Weigel1,2 and Oliver Bieri1,2

1Radiology, Radiological Physics, University Hospital Basel, Basel, Switzerland, 2Dept. of Biomedical Engineering, University of Basel, Basel, Switzerland

The potential of high resolution steady state diffusion and magnetization transfer (MT) imaging approaches with short acquisition times of less than 2min were investigated for the depiction of the spinal cord. As a surprising result, diffusion weighted time-reversed fast imaging with steady state precession (PSIF) sequences are not able to generate notable diffusion based contrast in the spinal cord (identical diffusion quotient DQ = 1.96+-0.20). High resolution balanced steady state free precession (bSSFP) sequences, however, are able to depict MT induced signal saturation in spinal cord white matter (MT ratio = 0.30+-0.07).

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