Abstract #4097

Patterns of Microstructural Correlations in the White Matter of the Neonatal Brain

Douglas C Dean III^1,2, Elizabeth M Planalp^1,3, William Wooten², Nagesh Adluru¹, H Hill Goldsmith^1,3, Richard J Davidson^1,2,3,4, and Andrew L Alexander^1,4,5

¹Waisman Center, University of Wisconsin-Madison, Madison, WI, United States, ²Center for Healthy Minds, University of Wisconsin-Madison, Madison, WI, United States, ³Psychology, University of Wisconsin-Madison, Madison, WI, United States, ⁴Psychiatry, University of Wisconsin-Madison, Madison, WI, United States, ⁵Medical Physics, University of Wisconsin-Madison, Madison, WI, United States

Quantitative MRI affords a unique opportunity to map dynamic patterns of neurodevelopment and provide insight into relations between brain maturation and emerging cognition. Using a data-driven technique, we investigated underlying patterns of white matter microstructure and subsequently examined the relationships of these microstructural correlations with respect to gestation-corrected age. We demonstrate that patterns of white matter development may be informative to studies of early brain development.

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