Resting-state fMRI has been widely used to investigate the functional deficits of Alzheimer's disease (AD) and mild cognitive impairment (MCI). In this study, we applied this method to investigate the differences in tissue perfusion deficits between MCI, AD, and normal control (NC) groups. The results show that the AD and MCI groups have areas with less fast perfusion than normal controls. While the MCI group has more perfusion deficits in the frontal lobe, the AD group has more perfusion deficits in the parietal and occipital lobe.
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