Abstract #4183

Evaluation of intravoxel incoherent motion in pituitary adenoma using turbo spin-echo diffusion-weighted imaging

Kiyohisa Kamimura¹, Masanori Nakajo¹, Yoshihiko Fukukura¹, Shingo Fujio², Takashi Iwanaga³, Tomoyuki Okuaki ⁴, and Takashi Yoshiura¹

¹Radiology, Kagoshima University Medical and Dental Hospital, Kagoshima, Japan, ²Neurosurgery, Kagoshima University Medical and Dental Hospital, Kagoshima, Japan, ³Clinical Engineering Department Radiation Section, Kagoshima University Hospital, Kagoshima, Japan, ⁴Philips Healthcare, Tokyo

Our purpose was to evaluate the intravoxel incoherent motion (IVIM) in the pituitary adenoma using turbo spin-echo diffusion-weighted imaging (TSE-DWI). The f (perfusion fraction) in the pituitary adenoma was significantly lower than that in the normal pituitary gland, which is consistent with histopathologically known lower microvascular density in adenomas compared to normal pituitary tissue. There was no significant correlation between the f and the volume in pituitary adenomas. TSE-DWI-based IVIM imaging is a viable imaging technique for assessment of vascularity in skull base lesions including pituitary adenoma.

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