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Abstract #4184

Histogram Analysis of Intravoxel Incoherent Motion in Peritumoral Edema for Distinguishing between Central Nervous System Lymphoma and Other Brain Tumors

Kazuhiro Murayama1, Takashi Fukuba2, Shigeharu Ohyu3, Ayako Ninomiya3, Kazuhiro Katada4, and Hiroshi Toyama1

1Radiology, Fujita Health University, Toyoake, Japan, 2Radiology, Fujita Health University Hospital, Toyoake, Japan, 3Toshiba Medical Systems Corporation, Japan, 4Joint Research Laboratory of Advanced Medical Imaging, Fujita Health University, Toyoake, Japan

Additional benefits of quantitative analysis of peritumoral edema for distinguishing between brain tumors by diffusion weighted image or dynamic susceptibility contrast MRI has been described. Our aim was to investigate the hypothesis that quantitative analysis of intravoxel incoherent motion (IVIM) in peritumoral edema may be a useful parameter for distinguishing between central nervous system lymphoma (CNSL) and other brain tumors. Quantitative analysis of IVIM indicates that D* and f maps of CNSL visually showed increase values in peritumoral edema. Our results indicate that these IVIM parameters have been successfully applied to obtain quantitative estimates of the vascularity and perfusion in peritumoral edema for differenciating CNSL and others without gadolinium contrast agent.

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