Meeting Banner
Abstract #4274

Quantification of Brain Metabolites in Alcohol Dependent Patients Using MRS with Experimental Basis Sets at 3T

Hyeon-Man Baek1,2 and Yeong-Jae Jeon1,2

1Korea Basic Sicence Institute, Ochang, Korea, Republic of, 2Dept. Bio-Analytical Science, Univ of Science & Technology, Daejeon, Korea, Republic of

In this study, in vivo quantification of brain metabolites measured on the dorsolateral prefrontal cortex (DLPFC) was carried out with LCModel using a priori knowledge based on experiment metabolite basis set signals. The main observation in this work was the significant reduction of tCho and Ins, and increase of GSH and Glx concentrations in the left DLPFC of alcohol dependent patients compared to healthy control subjects.

This abstract and the presentation materials are available to members only; a login is required.

Join Here