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Abstract #4379

Differential diagnosis of hepatocellular carcinoma and hepatic metastases using Radiomics Features from Quantitative DCE-MRI

Ye Li1, Lian Ai Liu, Ning Huang2, and Yan Guo2

1First Affiliated Hospital of Dalian Medical University, Dalian, People's Republic of China, 2GE Healthcare, Lifescience, China

To evaluate the value of Ktrans and HPI (hepatic arterial perfusion index), and their radiomics features in the differential diagnosis of hepatocellular carcinoma (HCC) and hepatic metastases from colorectal cancer (HM) using dynamics contrast enhanced MRI (DCE-MRI). Exchange model with dual input-based arterial input function was used to obtain the radiomics features that can provide a comprehensive assessment of tumors’ physiologic properties including vascular permeability, microcirculation and hemodynamic information. Our results indicated that IDM (Ktrans), inertia and correlation (HPI) are of great significance to differentiate HM and HCC.

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