Meeting Banner
Abstract #4495

Intrinsic susceptibility MRI detects phenotypic alteration induced by a potent anaplastic lymphoma kinase inhibitor in a transgenic model of neuroblastoma

Yann Jamin1, Elizabeth R. Tucker2, Evon Poon2, Alexander Koers2, Laura S. Danielson2, Louis Chesler2, and Simon P. Robinson1

1Division of Radiotherapy and Imaging, The Institute of Cancer Research, London, London, United Kingdom, 2Division of Cancer Therapeutics and Division of Clinical Studies, The Institute of Cancer Research, London, London, United Kingdom

In this study we demonstrate that the transverse relaxation rate R2* affords a biomarker of response to a potent anaplastic lymphoma kinase inhibitor in the Th-ALKF1174L/Th-MYCN genetically engineered murine model of neuroblastoma, a childhood cancer of the nervous system

This abstract and the presentation materials are available to members only; a login is required.

Join Here