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Abstract #4509

Optimized Fast High-Resolution Whole-Body Imaging Protocols for Clincial Oncologic PET/MRI

Simone Angela Winkler1, Anne Muehe1, Ashok Theruvath1, Maryam Aghighi1, Sandra Luna-Fineman1, Neyssa Marina1, Ranjana Advani1, Valentina Taviani2, Samantha J Holdsworth1, Praveen Gulaka1, and Heike Daldrup-Link1

1Stanford University, Stanford, CA, United States, 2GE Healthcare

We present a fast sequence with high diagnostic accuracy to move towards high-throughput clinical whole-body cancer staging using PET/MRI. Ferumoxytol-contrast enhanced T1-weighted LAVA-Flex is acquired at 16s/bed, at a voxel size of 3.4x1.5x1.9mm. This contrast-enhanced sequence offers superior vessel contrast and resolution to existing T1 co-registration modalities that are most commonly based on MR attenuation correction sequences or longer T1-weighted sequences. Integration of this sequence in a clinical protocol bears the promise of dramatically accelerated whole-body cancer staging with durations <20min, thus offering similar exam times to the more radiation-invasive alternative of PET/CT.

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