Abstract #4524

Increased regional cerebral venous oxygen saturation in mild traumatic brain injury is correlated with neurophysiological function: a magnetic susceptibility mapping study

Chao Chai¹, Chao Zuo², Linlin Fan, Tianyi Qian, E Mark Haacke, Shuang Xia, and Wen Shen

¹Radiology Department, Tianjin First Central Hospital, Tianjin, People's Republic of China, ²Department of Nuclear Medicine, Cangzhou Central Hospital

The aim of this study is to explore the changes of regional cerebral venous oxygen saturation (SvO₂) in patients with mild traumatic brain injury (mTBI) using susceptibility mapping (SWIM). SWIM was reconstructed from magnitude and phase data of SWI to measure the susceptibility of cerebral veins in mTBI patients and healthy controls. The results suggested that overall regional cerebral SvO₂ was higher in mTBI patients than controls. The regional cerebral SvO₂ shows that decreased to normal levels along with an increase in elapsed time post trauma and a high-SvO₂ condition is an evidence of neurophysiological deficit.

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