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Abstract #4558

MR Fingerprinting in paediatric neuroradiology: our initial experience

Graziella Donatelli1, Guido Buonicontri2, Rosa Pasquariello3, Mauro Costagli2, Raffaello Canapicchi3, and Michela Tosetti2,3

1Università di Pisa, Pisa, Italy, 2IMAGO7 Research Institute, 3IRCCS Stella Maris, Pisa Italy

In paediatric neuroimaging, young children have often to be sedated in order to obtain diagnostic MRI images. Magnetic Resonance Fingerprinting (MRF) is a potential alternative to sedation in children, as it achieves a fast exam with reduced sensitivity to patient motion. MRF acquisitions can be used to acquire a fully-quantitative anatomical exam in less than five minutes at a standard resolution. We performed a preliminary evaluation of MRF in 15 paediatric patients, acquiring both the standard protocol and MRF at 1.5T. Detection of brain alterations was possible, if present, in all patients. Only a few small lesions were unrevealed. MRF could be a promising tool for a fast and diagnostic exam in children, and due to its low sensitivity to motion it has the potential to allow exams without sedation.

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