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Abstract #4559

Contrast Agent-Induced High Signal Intensity in Dentate Nucleus on Unenhanced T1-Weighted Images: Comparison of Gadodiamide and Gadoxetic Acid

Shintaro Ichikawa1, Utaroh Motosugi1, Yoshie Omiya1, and Hiroshi Onishi1

1Department of Radiology, University of Yamanashi, Chuo-shi, Japan

Hyperintensity in the dentate nucleus (DN) on unenhanced T1-weighted images was associated with previous administration of gadodiamide but not gadoxetic acid. There were no significant differences in DN-to-pons ratio between patients who received five or more administrations of gadoxetic acid and those without gadolinium-based contrast agent administration or chronic liver disease. Hyperintensity in the dentate nucleus on unenhanced T1-weighted images is not associated with up to fifteen previous administrations of gadoxetic acid. Therefore, gadolinium deposition in the brain might be difficult despite a history of repeated gadoxetic acid administration.

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