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Abstract #4618

Evaluation of water permeability for ischemic lesion in the brain using DW-ASL

Noriyuki Fujima1, Tomoyuki Okuaki, Takuya Aoike, Suzuko Aoike, and Kohsuke Kudo

1Hokkaido University Hospital, Sapporo, Japan

Diffusion-weighted arterial spin labeling technique was described to depict the tissue water permeability in the brain non-invasively; this information was also described to reflect the degree of blood-brain barrier damage. This study revealed that tissue water permeability can be useful for the evaluation of ischemic lesion more in detail than conventional technique such as T2WI or FLAIR for the determination of severity of ischemia and the prediction how fast the ischemia will progress.

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