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Abstract #4620

Clinical application of Half Fourier Acquisition Single Shot Turbo Spin Echo (HASTE) imaging with multiband (MB) excitation and PINS refocusing pulses

Jenni Schulz1, José P. Marques1, Annemieke ter Telgte1, Frank-Erik de Leeuw1,2, Frederick J.A. Meijer3, and David G. Norris1,4

1Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, Netherlands, 2Department of Neurology, Radboud University Medical Centre, Nijmegen, Netherlands, 3Department of Radiology and Nuclear Medicine, Radboud University Medical Centre Nijmegen, Nijmegen, Netherlands, 4Erwin L. Hahn Institute for Magnetic Resonance Imaging, University Duisburg-Essen, Essen, Germany

In this abstract, we demonstrate a clinical application of a MB-PINS-HASTE sequence with TRAPS and compare it to a standard HASTE protocol which is used in daily clinical practice. The modified MB-PINS-HASTE sequence offers the possibility to overcome limitations related to its typically high energy deposition and can accelerate the acquisition by acquiring several slices simultaneously. The reconstructed images show good diagnostic quality for the evaluation of the overall brain and CSF spaces in patients with small vessel disease. MB-PINS HASTE therefore offers the possibility of using ultrafast spin-echo imaging to acquire anatomical T2-weighted images and follow dynamic signal changes.

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