Abstract #4668

Semi-quantitative Parametric Evaluation of Parotid Gland Function Using Proton Density Magnetic Resonance Imaging

Yu-Chia Cheng¹, Yi-Jui Liu², Yi-Hsiung Lee^3,4, Hing-Chiu Chang⁵, Hui-Chu Chiu⁶, Ta-Wei Chiu⁷, Kang Hsu⁸, Hsian-He Hsu^4,9, and Chun-Jung Juan^4,9

¹Master 's Program of Biomedical Informatics and Biomedical Engineering of Feng Chia University, Taichung, Taiwan, Taichung, Taiwan, ²Department of Automatic Control Engineering, Feng Chia University, Taichung, Taiwan, Republic of China, ³Ph.D. program in Electrical and Communication Engineering in Feng Chia University, Taichung, Taiwan, Republic of China, ⁴Department of Radiology, Tri-Service General Hospital, Taipei, Taiwan, Republic of China, ⁵Department of Diagnostic Radiology, The University of Hong Kong, Hong Kong, ⁶Ph.D. program of Technology Management, Chung Hua University, Hsinchu, Taiwan, Republic of China, ⁷Department of Medicine, Taipei Medical University, Taipei, Taiwan, Republic of China, ⁸Department of Dentistry, National Defense Medical Center, Taipei, Taiwan, Republic of China, ⁹Department of Radiology, National Defense Medical Center, Taipei, Taiwan, Republic of China

The parotid gland function is evaluated by gustatory stimulation using scintigraphy in clinic. It is supposed to measure the water component of parotid gland using PD MRI instead of scintigraphy. In this study, we initially developed the evaluation of parotid gland function by PD MRI, and 10 healthy volunteers underwent double echo EPI with gustatory stimulation. Maximal drop ratio (MDR), time to peak (TTP), drop slope (DS), recovery slope (RS) and recovery ratio (RR) were calculated. The signal intensity dropped significantly after gustatory stimulation on PD image (P<0.01). MRI allows quantification of parotid gland function using semi-quantitative functional parameters.

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