Abstract #4669

3D pituitary dynamic MR imaging using the TWIST and Iterative reconstruction TWIST

Yusuke Yokota¹, Yasutaka Fushimi¹, Tomohisa Okada², Akira Yamamoto¹, Tsutomu Okada¹, Aurelien Stalder³, Christoph Forman³, Michaela Schmidt³, and Kaori Togashi¹

¹Department of Diagnostic Imaging and Nuclear Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan, ²Human Brain Research Center, Graduate School of Medicine, Kyoto University, Kyoto, Japan, ³Siemens Healthcare GmbH, Erlangen, Germany

The aim of this study is to perform a comparison between 3D pituitary dynamic study using time-resolved angiography with interleaved stochastic trajectories (TWIST) and TWIST with iterative reconstruction (IT-TWIST). IT-TWIST was retrospectively reconstructed from the raw data of TWIST by using L1 wavelet regularization in space and time. One neuroradiologist put regions of interest in pituitary stalk and anterior lobe and made time intensity curve. The slope of enhancement in the early phase was evaluated. In addition, image quality was visually evaluated. IT-TWIST yielded higher slope of enhancement in the early phase in anterior lobe and better image quality.

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