Meeting Banner
Abstract #4675

Feasibility of Grey Matter and White Matter Segmentation of the Conus Medullaris: A Pilot In Vivo Investigation in the Neurologically Intact Spinal Cord

Martina D Liechti1,2, Nuttakarn Budtarad1, Daniel R Altmann1,3, Xixi Yang1,2, Ahmed T Toosy1, Jalesh N Panicker2, Claudia AM Gandini Wheeler-Kingshott1, and Marios Yiannakas1

1UCL Institute of Neurology, Queen Square MS Centre, University College London, London, United Kingdom, 2UCL Institute of Neurology, Uro-Neurology, Department of Brain Repair & Rehabilitation, University College London, London, United Kingdom, 3Translational Imaging Group, Centre for Medical Image Computing, Department of Medical Physics and Biomedical Engineering, University College London, London, United Kingdom

Spinal cord (SC) atrophy as a consequence of neurodegeneration, and its association with clinical scores of disability, may be assessed indirectly by means of cord, grey matter (GM) and white matter (WM) segmentation from magnetic resonance images. Neuropathological evidence suggests that in certain neurological conditions, early degeneration may occur as low as the sacral SC, potentially implicating neural pathways that are essential for the functioning of the lower urinary tract. In this work, the feasibility of GM/WM segmentation of the conus medullaris is assessed in vivo using a clinical 3T system.

This abstract and the presentation materials are available to members only; a login is required.

Join Here